CHEM 1:
Structure and Reactivity
First lecture class in summer organic series. Organic chemistry, functional groups, hydrocarbons, stereochemistry, thermochemistry, kinetics and chemical equilibria. Recitation. Prerequisite: 31 A, B or 31 X or an AP Chemistry score of 5.
Terms: Sum
| Units: 4
CHEM 1L:
Introduction to Organic Chemistry Lab
Techniques for separation of compounds: distillation, crystallization, extraction and chromatographic procedures in the context of reactions learned in Chem 1. Use of GC instrumentation for the analysis of reactions. Lecture treats theory; lab provides practice. Prerequisite: Chem 33 or Chem 1 co-requisite.
Terms: Sum
| Units: 2
CHEM 2:
Organic Monofunctional Compounds
Second lecture class in summer organic series. Organic chemistry of oxygen and nitrogen aliphatic compounds. Recitation. Prerequisite: Chem 33 or Chem 1.
Terms: Sum
| Units: 4
CHEM 2L:
Organic Chemistry Lab I
Application of separation techniques in the context of reactions learned in Chem 2. Use of IR instrumentation for the analysis of reactions. Lecture treats theory; lab provides practice. Prerequisite: Chem 1L. Co-requisite: Chem 35 or Chem 2. Course equivalent in conjunction with Chem 3L: Chem 130
Terms: Sum
| Units: 2
CHEM 3:
Organic Polyfunctional Compounds
Last lecture class in summer organic series. Aromatic compounds, polysaccharides, amino acids, proteins, natural products, dyes, purines, pyramidines, nucleic acids and polymers. Recitation. Prerequisite: Chem 35 or Chem 2. Course equivalent: Chem 131.
Terms: Sum
| Units: 4
CHEM 3L:
Organic Chemistry Lab II
Qualitative and analytical techniques applied to reactions learned in Chem 3. Use of NMR instrumentation for the analysis of reactions. Lecture treats theory; lab provides practice. Prerequisite: Chem 2L. Co-requisite: Chem 131 or Chem 3. Course equivalent in conjunction with Chem 2L: Chem 130
Terms: Sum
| Units: 2
CHEM 4:
Biochemistry: Chemistry of Life
A four-week intensive biochemistry course from a chemical perspective. The chemical basis of life, including the biomolecular chemistry of amino acids, proteins, carbohydrates, lipids, and nucleic acids, as well as enzyme kinetics and mechanisms, thermodynamics, and core metabolism, control, and regulation. Recitation includes group work on case studies that support the daily lecture material. Prerequisites: CHEM 33, 35, 131 or 1 year of organic chemistry; Math 19, 20, 21 or 41, 42 or 1 year of single variable calculus.
Terms: Sum
| Units: 4
CHEM 10:
Exploring Research and Problem Solving Across the Sciences
Development and practice of critical problem solving and study skills using wide variety of scientific examples that illustrate the broad yet integrated nature of current research. Student teams will have the opportunity to explore and present on topics revolving around five central issues: energy, climate change, water resources, medicine, and food & nutrition from a chemical perspective. Course offered in August prior to start of fall quarter.
Terms: Aut
| Units: 2
CHEM 25N:
Science in the News
Preference to freshmen. Possible topics include: diseases such as avian flu, HIV, and malaria; environmental issues such as climate change, atmospheric pollution, and human population; energy sources in the future; evolution; stem cell research; nanotechnology; and drug development. Focus is on the scientific basis for these topics as a basis for intelligent discussion of societal and political implications. Sources include the popular media and scientific media for the nonspecialist, especially those available on the web.
Terms: Aut
| Units: 3
| UG Reqs: WAY-SMA
CHEM 26N:
The What, Why, How and wow's of Nanotechnology
Preference to freshmen. Introduction to nanotechnology with discussion of basic science at the nanoscale, its difference from molecular and macroscopic scales, and implications and applications. Developments in nanotechnology in the past two decades, from imaging and moving single atoms on surfaces to killing cancer cells with nanoscale tools and gadgets.
Terms: Spr
| Units: 3
| UG Reqs: GER: DB-NatSci
CHEM 27N:
Light and Life
Preference given to freshman. Light plays a central role in many biological processes and color affects everything in our world. This includes familiar processes such as photosynthesis and vision, but also proton pumps in the organisms that make the Bay purple, green fluorescent protein (GFP), the light from fireflies, the blue and red light receptors responsible for directing how plants grow, the molecules responsible for fall colors, and repair enzymes such as DNA photolyase (this year¿s Nobel prize). Light is also used to interrogate (e.g. super-resolution microscopy, last year¿s Nobel prize) and manipulate (optogenetics) biological systems. Light causes sunburn, but can also be used in combination with special molecules to treat diseases. We will discuss the nature of light, how it is measured, how it is generated in the laboratory, how molecules are excited, and how one measures the fate of this excitation. Chem 31X or 31A preferred, but not required.
Terms: Spr
| Units: 3
CHEM 28N:
Science Innovation and Communication
Preference to freshmen. The course will explore evolutionary and revolutionary scientific advances; their consequences to society, biotechnology, and the economy; and mechanisms for communicating science to the public. The course will engage academic and industrial thought leaders and provide an opportunity for students to participate in communicating science to the public.
Terms: Aut
| Units: 3
CHEM 31A:
Chemical Principles I
For students with moderate or no background in chemistry. Stoichiometry; periodicity; electronic structure and bonding; gases; enthalpy; phase behavior. Emphasis is on skills to address structural and quantitative chemical questions; lab provides practice. Recitation.
Terms: Aut, Sum
| Units: 5
| UG Reqs: GER: DB-NatSci, WAY-SMA
CHEM 31AC:
Problem Solving in Science
Development and practice of critical problem solving skills using chemical examples. Limited enrollment. Prerequisite: consent of instructor. Corequisite: CHEM 31A.
Terms: Aut
| Units: 1
CHEM 31B:
Chemical Principles II
Chemical equilibrium; acids and bases; oxidation and reduction reactions; chemical thermodynamics; kinetics. Lab. Prerequisite: 31A.
Terms: Win, Sum
| Units: 5
| UG Reqs: GER: DB-NatSci, WAY-SMA
CHEM 31BC:
Problem Solving in Science
Development and practice of critical problem solving skills using chemicalnexamples. Students should also be concurrently enrolled in the parent course 31B. Limited enrollment and with permission of the instructor.
Terms: Win
| Units: 1
CHEM 31X:
Chemical Principles Accelerated
Accelerated; for students with substantial chemistry background. Chemical equilibria concepts, equilibrium constants, acids and bases, chemical thermodynamics, quantum concepts, models of ionic and covalent bonding, atomic and molecular orbital theory, periodicity, and bonding properties of matter. Recitation. Prerequisites: AP chemistry score of 5 or passing score on chemistry placement test, and AP Calculus AB score of 4 or Math 20 or Math 41. Recommended: high school physics.
Terms: Aut
| Units: 5
| UG Reqs: GER: DB-NatSci, WAY-SMA
CHEM 33:
Structure and Reactivity
Organic chemistry, functional groups, hydrocarbons, stereochemistry, thermochemistry, kinetics, chemical equilibria. Recitation. Prerequisite: 31A,B, or 31X, or an AP Chemistry score of 5.
Terms: Win, Spr
| Units: 5
| UG Reqs: GER: DB-NatSci, WAY-SMA
CHEM 33C:
Problem Solving in Science
Development and practice of critical problem solving skills using chemical examples. Limited enrollment. Prerequisite: consent of instructor. Corequisite: CHEM 33.
Terms: Spr
| Units: 1
CHEM 35:
Synthetic and Physical Organic Chemistry
The structure and reactivity of mono- and polyfunctionalized molecules; retrosynthetic analysis and multi-step chemical synthesis. Course will emphasize deductive logic and reasoning skills through conceptual learning. Students gain an appreciation for the profound impact of organic chemistry on humankind in fields ranging from biology and medicine to gastronomy, agriculture, and materials science. A three hour lab section provides hands on experience with modern chemical methods for preparative and analytical chemistry. Prerequisite: Chem 33
Terms: Aut, Spr
| Units: 5
| UG Reqs: GER: DB-NatSci
CHEM 110:
Directed Instruction/Reading
Undergraduates pursue a reading program under supervision of a faculty member in Chemistry; may also involve participation in lab. Prerequisites: superior work in 31A,B, 31X, or 33; and consent of instructor.
Terms: Aut, Win, Spr, Sum
| Units: 1-2
| Repeatable
4 times
(up to 8 units total)
Instructors: ;
Bao, Z. (PI);
Bent, S. (PI);
Bertozzi, C. (PI);
Boxer, S. (PI);
Burns, N. (PI);
Cegelski, L. (PI);
Chen, J. (PI);
Chidsey, C. (PI);
Cimprich, K. (PI);
Cui, B. (PI);
Cui, Y. (PI);
Dai, H. (PI);
Du Bois, J. (PI);
Fayer, M. (PI);
Frank, C. (PI);
Herschlag, D. (PI);
Hodgson, K. (PI);
Kanan, M. (PI);
Karunadasa, H. (PI);
Khosla, C. (PI);
Kool, E. (PI);
Markland, T. (PI);
Martinez, T. (PI);
Moerner, W. (PI);
Pande, V. (PI);
Pecora, R. (PI);
Rao, J. (PI);
Solomon, E. (PI);
Stack, D. (PI);
Trost, B. (PI);
Wandless, T. (PI);
Waymouth, R. (PI);
Wender, P. (PI);
Xia, Y. (PI);
Zare, R. (PI);
Derner, T. (GP);
Frank, D. (GP)
CHEM 111:
Exploring Chemical Research at Stanford
Preference to freshmen and sophomores. Department faculty describe their cutting-edge research and its applications.
Terms: Win
| Units: 1
CHEM 130:
Organic and Bio-organic Chemistry Laboratory
Intermediate organic and bio-organic chemistry laboratory, including synthesis and spectroscopy. Nobel prize winning reactions and characterization techniques, such as Diels-Alder and modified Wittig reactions, as well as IR, NMR, and GCMS; Biodiesel synthesis and lipid characterization. Prerequisite: Chem 35 taken in Aut 2014-15 or later, or Chem 35 and 36. Corequisite: 131.
Terms: Aut, Win
| Units: 3
| UG Reqs: GER: DB-NatSci
CHEM 131:
Organic Polyfunctional Compounds
Aromatic compounds, polysaccharides, amino acids, proteins, natural products, dyes, purines, pyrimidines, nucleic acids, and polymers. Prerequisite: 35.
Terms: Aut, Win
| Units: 3
| UG Reqs: GER: DB-NatSci
CHEM 132:
Synthesis Laboratory
Focus is on longer syntheses with an emphasis upon using metal catalysts. Emphasis will be on complete characterization of final products using chromatographic and spectroscopic methods. Concludes with an individual synthesis project. Prerequisites: 35, 130.
Terms: Win
| Units: 3
| UG Reqs: GER: DB-NatSci
CHEM 134:
Analytical Chemistry Laboratory
Classical analysis methods, statistical analyses, chromatography, and spectroscopy will be covered with an emphasis upon quantitative measurements and data analysis. WIM course with full lab reports and oral communication. Concludes with student-developed quantitative project. Prerequisite: Chem 35
Terms: Spr
| Units: 5
| UG Reqs: GER: DB-NatSci, WAY-AQR, WAY-SMA
CHEM 135:
Physical Biochemistry
Introduction to the physical principles that underlie biological function for students in the life sciences. Chemical thermodynamics: first, second and third laws, heat & work, entropy, free energy, chemical equilibrium, physical equilibrium, osmotic pressure, other colligative properties. Chemical kinetics: rate laws, integration of rate laws, reaction mechanisms, enzyme kinetics. Applications to proteins, lipids, nucleic acids, carbohydrates, small molecules, and macromolecular assemblies. Prerequisites: 31A,B, or 31X, 33, 35 & calculus.
Terms: Win
| Units: 3
| UG Reqs: GER: DB-NatSci
CHEM 137:
Special Topics in Synthesis
The course covers the basic toolbox for construction of more complex structures for function, largely directed towards molecules of biological relevance. The focus will be the ability to perform structural changes efficiently in order to enable the design of the best structure for a function. The concepts of catalytic processes are at the heart of the how small molecule drug discovery is performed. Fundamentals of the pertinent catalytic processes are discussed. The inter-relationship of synthetic chemistry and pharmaceuticals is emphasized. See more at: http://library.stanford.edu/guides/chem-137-special-topics-organic-chemistry#sthash.vi9khNU5.dpuf. Prerequisite CHEM 35.
Terms: Spr
| Units: 3
| UG Reqs: GER: DB-NatSci
CHEM 150:
Single-Crystal X-ray Diffraction (CHEM 250)
Practical X-ray crystallography of discrete molecules, which will emphasize crystal growth, measurement strategies, structure solution and refinement, and report generation. Example structures will include absolute configuration of organic compounds containing only second row atoms, metal containing complexes, and small molecule compounds with disorder. Students will gain knowledge of the underlying theory and concepts for each step of x-ray structural determination.
Terms: Aut
| Units: 3
CHEM 151:
Inorganic Chemistry I
Theories of electronic structure, stereochemistry, and symmetry properties of inorganic molecules. Topics: ionic and covalent interactions, electron-deficient bonding, and molecular orbital theories. Emphasis is on the chemistry of the metallic elements. Prerequisites: 35. Recommended: 171.
Terms: Win
| Units: 3
| UG Reqs: GER: DB-NatSci
CHEM 153:
Inorganic Chemistry II
The theoretical aspects of inorganic chemistry. Group theory; many-electron atomic theory; molecular orbital theory emphasizing general concepts and group theory; ligand field theory; application of physical methods to predict the geometry, magnetism, and electronic spectra of transition metal complexes. Prerequisites: 151, 173.
Terms: Spr
| Units: 3
| UG Reqs: GER: DB-NatSci
CHEM 155:
Advanced Inorganic Chemistry (CHEM 255)
Chemical reactions of organotransition metal complexes and their role in homogeneous catalysis. Analogous patterns among reactions of transition metal complexes in lower oxidation states. Physical methods of structure determination. Prerequisite: one year of physical chemistry.
Terms: Spr
| Units: 3
CHEM 171:
Physical Chemistry I
Chemical thermodynamics and kinetic molecular models; gases, phase changes, solutions and chemical equilibrium, chemical kinetics; roles of thermal motion and energy barriers, relationship between reaction mechanism and rate. The MATLAB programming language will be used for modeling, analysis and visualization throughout. Optional discussion section. Prerequisites: 31A,B, or 31X; 33; PHYS 41; either CME 100 or MATH 51 and (MATH 51M or CME 192 or CS 106A).
Terms: Spr
| Units: 3
| UG Reqs: GER: DB-NatSci
CHEM 173:
Physical Chemistry II
Introduction to quantum chemistry: the basic principles of wave mechanics, the harmonic oscillator, the rigid rotator, infrared and microwave spectroscopy, the hydrogen atom, atomic structure, molecular structure, valence theory. Prerequisites: CHEM 171; CME 102, 104 or MATH 53; PHYSICS 41, 43.
Terms: Aut
| Units: 3
| UG Reqs: GER: DB-NatSci
CHEM 174:
Electrochemical Measurements Lab (CHEM 274)
Introduction to modern electrochemical measurement in a hands-on, laboratory setting. Students assemble and use electrochemical cells including indicator, reference, working and counter electrodes, with macro, micro and ultramicro geometries, salt bridges, ion-selective membranes, electrometers, potentiostats, galvanostats, and stationary and rotated disk electrodes. The later portion of the course will involve a student-generated project to experimentally characterize some electrochemical system. Prerequisites: 134, 171, MATH 51, PHYSICS 44 or equivalent.
Terms: Aut
| Units: 3
| UG Reqs: GER: DB-NatSci
CHEM 175:
Physical Chemistry III
Molecular theory of kinetics and statistical mechanics: transport and reactions in gases and liquids, ensembles and the Boltzmann distribution law, partition functions, molecular simulation, structure and dynamics of liquids. Diffusion and activation limited reactions, potential energy surfaces, collision theory, transition-state theory and Marcus theory of reaction rates. Prerequisites: 171, 173.
Terms: Win
| Units: 3
| UG Reqs: GER: DB-NatSci
CHEM 176:
Spectroscopy Laboratory
Use of spectroscopic instrumentation to study molecular properties and physical chemical time-dependent processes. Experiments include electronic ultraviolet/visible absorption, fluorescence, Raman, infrared vibrational and nuclear magnetic resonance spectroscopies. Prerequisite: 173.
Terms: Win
| Units: 3
| UG Reqs: GER: DB-NatSci
CHEM 181:
Biochemistry I (BIO 188, CHEMENG 181, CHEMENG 281)
Structure and function of major classes of biomolecules, including proteins, carbohydrates and lipids. Mechanistic analysis of properties of proteins including catalysis, signal transduction and membrane transport. Students will also learn to critically analyze data from the primary biochemical literature. Satisfies Central Menu Area 1 for Bio majors. (CHEMENG offerings formerly listed as 188/288.) Prerequisites: CHEM 33, 35, 131, and 135 or 171.
Terms: Aut
| Units: 3
| UG Reqs: GER: DB-NatSci
CHEM 183:
Biochemistry II (BIO 189, CHEMENG 183, CHEMENG 283)
Focus on metabolic biochemistry: the study of chemical reactions that provide the cell with the energy and raw materials necessary for life. Topics include glycolysis, gluconeogenesis, the citric acid cycle, oxidative phosphorylation, photosynthesis, the pentose phosphate pathway, and the metabolism of glycogen, fatty acids, amino acids, and nucleotides as well as the macromolecular machines that synthesize RNA, DNA, and proteins. Medical relevance is emphasized throughout. Satisfies Central Menu Area 1 for Bio majors. Prerequisite: BIO 188/288 or CHEM 181 or CHEMENG 181/281 (formerly 188/288).
Terms: Win
| Units: 3
| UG Reqs: GER: DB-NatSci
CHEM 184:
Biological Chemistry Laboratory
Modern techniques in biological chemistry including protein purification, characterization of enzyme kinetics, heterologous expression of His-tagged fluorescent proteins, site-directed mutagenesis, and single-molecule fluorescence microscopy. Prerequisite: 181.
Terms: Spr
| Units: 4
| UG Reqs: GER: DB-NatSci
CHEM 185:
Biophysical Chemistry
Primary literature based seminar/discussion course covering classical and contemporary papers in biophysical chemistry. Topics include: protein structure and stability, folding, single molecule fluorescence and force microscopy, simulations, ion channels, GPCRs, and ribosome structure/function. Prerequisites: 171 and 181.
Terms: Spr
| Units: 3
| UG Reqs: GER: DB-NatSci
CHEM 187:
Chemistry of Posttranslational Modification of Proteins (CHEM 287)
This short course runs for the first four weeks of the quarter, January only. This course examines the chemical principles and mechanisms of major classes of covalent PTMs. Up to 2000 enzyme catalysts are dedicated to PTM creation and reversal, including phosphorylations, acylations, alkylations, glycosylations, oxygenations, automodifications such as green fluorescent protein formation, and controlled proteolysis, including protein splicing. The different PTM chemistries both constrain and enable the diverse biological functions of modified protein substrates. Prerequisite: Chem 181 or equivalent.
Last offered: Winter 2015
| Units: 1
| Repeatable
2 times
(up to 2 units total)
CHEM 187A:
Antibiotics: Actions, Origins, Resistance (CHEM 287A)
This course provides a chemocentric view of three central aspects of antibiotics: (1) antibiotics can come from natural microbial sources or by medicinal chemistry efforts; (2) the mechanism of action of types of clinically used antibiotics towards five major target classes in pathogenic bacteria are assessed; (3) the widespread utilization of antibiotics selects for resistant bacterial pathogens: resistance mechanisms and possible solutions for next generation pathogens are addressed. This short course runs for the first five weeks of the quarter, from January through the first week of February. Prerequisite: Chem 181 or equivalent.
Terms: Win
| Units: 1
| Repeatable
3 times
(up to 3 units total)
CHEM 190:
Advanced Undergraduate Research
Limited to undergraduates who have completed Chem 35 and/or Chem 134, or by special arrangement with a faculty member. May be repeated 8 times for a max of 27 units. Prerequisite: 35 or 134. Corequisite: 300.
Terms: Aut, Win, Spr, Sum
| Units: 1-5
| Repeatable
9 times
(up to 27 units total)
Instructors: ;
Bao, Z. (PI);
Bent, S. (PI);
Bertozzi, C. (PI);
Boxer, S. (PI);
Burns, N. (PI);
Cegelski, L. (PI);
Chen, J. (PI);
Chidsey, C. (PI);
Cimprich, K. (PI);
Collman, J. (PI);
Cui, B. (PI);
Cui, Y. (PI);
Dai, H. (PI);
Du Bois, J. (PI);
Fayer, M. (PI);
Frank, C. (PI);
Herschlag, D. (PI);
Hodgson, K. (PI);
Huestis, W. (PI);
Kanan, M. (PI);
Karunadasa, H. (PI);
Khosla, C. (PI);
Kool, E. (PI);
Markland, T. (PI);
Martinez, T. (PI);
Moerner, W. (PI);
Pande, V. (PI);
Pecora, R. (PI);
Rao, J. (PI);
Solomon, E. (PI);
Stack, D. (PI);
Trost, B. (PI);
Wandless, T. (PI);
Waymouth, R. (PI);
Wender, P. (PI);
Xia, Y. (PI);
Zare, R. (PI);
Derner, T. (GP);
Frank, D. (GP)
CHEM 196:
Creating New Ventures in Engineering and Science-based Industries (CHEM 296, CHEMENG 196, CHEMENG 296)
Open to seniors and graduate students interested in the creation of new ventures and entrepreneurship in engineering and science intensive industries such as chemical, energy, materials, bioengineering, environmental, clean-tech, pharmaceuticals, medical, and biotechnology. Exploration of the dynamics, complexity, and challenges that define creating new ventures, particularly in industries that require long development times, large investments, integration across a wide range of technical and non-technical disciplines, and the creation and protection of intellectual property. Covers business basics, opportunity viability, creating start-ups, entrepreneurial leadership, and entrepreneurship as a career. Teaching methods include lectures, case studies, guest speakers, and individual and team projects.
Terms: Aut
| Units: 3
CHEM 200:
Research and Special Advanced Work
Qualified graduate students undertake research or advanced lab work not covered by listed courses under the direction of a member of the teaching staff. For research and special work, students register for 200.
Terms: Aut, Win, Spr, Sum
| Units: 1-15
| Repeatable
for credit
Instructors: ;
Bao, Z. (PI);
Bent, S. (PI);
Bertozzi, C. (PI);
Boxer, S. (PI);
Burns, N. (PI);
Cegelski, L. (PI);
Chen, J. (PI);
Chidsey, C. (PI);
Cimprich, K. (PI);
Collman, J. (PI);
Cui, B. (PI);
Cui, Y. (PI);
Dai, H. (PI);
Du Bois, J. (PI);
Fayer, M. (PI);
Frank, C. (PI);
Herschlag, D. (PI);
Hodgson, K. (PI);
Kanan, M. (PI);
Karunadasa, H. (PI);
Khosla, C. (PI);
Kool, E. (PI);
Markland, T. (PI);
Martinez, T. (PI);
Moerner, W. (PI);
Pande, V. (PI);
Rao, J. (PI);
Solomon, E. (PI);
Stack, D. (PI);
Trost, B. (PI);
Wandless, T. (PI);
Waymouth, R. (PI);
Wender, P. (PI);
Xia, Y. (PI);
Zare, R. (PI);
Derner, T. (GP);
Frank, D. (GP)
CHEM 221:
Advanced Organic Chemistry
Physical organic chemistry: molecular structures, bonding, and non-covalent interactions; thermodynamic and kinetic understanding of reactivity and reaction mechanism. Prerequisites: 137, 175.
Terms: Aut
| Units: 3
CHEM 223:
Advanced Organic Chemistry
Continuation of 221. Modern synthetic organic chemistry with an emphasis on structure, reactivity, and stereocontrol. Prerequisite: 221 or consent of instructor.
Terms: Win
| Units: 3
CHEM 225:
Advanced Organic Chemistry
Continuation of 223. Organic reaction science with an emphasis on mechanistic organic and organometallic chemistry, new synthetic methods, selectivity analysis, strategies for the design and synthesis of complex molecules, concepts for innovative problems solving and how to put these skills together in the generation of impactful ideas and proposals directed at solving problems in science. Prerequisite: 223 or consent of instructor.
Terms: Spr
| Units: 3
CHEM 225T:
Advanced Organic Chemistry
Organic reactions, new synthetic methods with special attention to catalysis and atom economy, selectivity analysis, and exercises in the syntheses of complex molecules.
Terms: Aut
| Units: 3
CHEM 227:
Therapeutic Science at the Chemistry - Biology Interface
Explores the design and enablement of new medicines that were born from a convergence of concepts and techniques from chemistry and biology. Topics include fundamental methods for biomolecule synthesis and engineering and application to hybrid chemical/biologic drugs, as well as modern approaches for target discovery and validation. Prerequisite: One year of undergraduate organic chemistry, as well as familiarity with concepts in biochemistry and molecular biology.
Terms: Spr
| Units: 3
CHEM 229:
Organic Chemistry Seminar
Required of graduate students majoring in organic chemistry. Students giving seminars register for 231.
Terms: Aut, Win, Spr
| Units: 1
| Repeatable
11 times
(up to 11 units total)
CHEM 231:
Organic Chemistry Seminar Presentation
Required of graduate students majoring in organic chemistry for the year in which they present their organic seminar. Second-year students must enroll all quarters.
Terms: Aut, Win, Spr
| Units: 1
| Repeatable
3 times
(up to 3 units total)
CHEM 233A:
Creativity in Organic Chemistry
Required of second- and third-year Ph.D. candidates in organic chemistry. The art of formulating, writing, and orally defending a research progress report (A) and two research proposals (B, C). Second-year students register for A and B; third-year students register for C. A: Aut, B: Spr, C: Spr
Terms: Aut
| Units: 1
CHEM 233B:
Creativity in Organic Chemistry
Required of second- and third-year Ph.D. candidates in organic chemistry. The art of formulating, writing, and orally defending a research progress report (A) and two research proposals (B, C). Second-year students register for A and B; third-year students register for C. A: Aut, B: Spr, C: Spr
Terms: Spr
| Units: 1
CHEM 233C:
Creativity in Organic Chemistry
Required of second- and third-year Ph.D. candidates in organic chemistry. The art of formulating, writing, and orally defending a research progress report (A) and two research proposals (B, C). Second-year students register for A and B; third-year students register for C. A: Aut, B: Spr, C: Spr
Terms: Spr
| Units: 1
CHEM 235:
Applications of NMR Spectroscopy
The uses of NMR spectroscopy in chemical and biochemical sciences, emphasizing data acquisition for liquid samples and including selection, setup, and processing of standard and advanced experiments.
Terms: Win
| Units: 3
CHEM 250:
Single-Crystal X-ray Diffraction (CHEM 150)
Practical X-ray crystallography of discrete molecules, which will emphasize crystal growth, measurement strategies, structure solution and refinement, and report generation. Example structures will include absolute configuration of organic compounds containing only second row atoms, metal containing complexes, and small molecule compounds with disorder. Students will gain knowledge of the underlying theory and concepts for each step of x-ray structural determination.
Terms: Aut
| Units: 3
CHEM 251:
Advanced Inorganic Chemistry
Primarily intended for first-year graduate students, as a review of some of the basic concepts in inorganic chemistry. Specific topics covered will include: symmetry, group theory, electronic structure of molecules and solids, and reactivity of coordination complexes. Prerequisite: Advanced undergraduate-level inorganic chemistry
Terms: Aut
| Units: 3
CHEM 253:
Advanced Inorganic Chemistry
Electronic structure and physical properties of transition metal complexes. Ligand field and molecular orbital theories, magnetism and magnetic susceptibility, electron paramagnetic resonance including hyperfine interactions and zero field splitting and electronic absorption spectroscopy including vibrational interactions. Prerequisite: 153 or the equivalent.
Last offered: Winter 2014
| Units: 3
CHEM 255:
Advanced Inorganic Chemistry (CHEM 155)
Chemical reactions of organotransition metal complexes and their role in homogeneous catalysis. Analogous patterns among reactions of transition metal complexes in lower oxidation states. Physical methods of structure determination. Prerequisite: one year of physical chemistry.
Terms: Spr
| Units: 3
CHEM 258A:
Research Progress in Inorganic Chemistry
Required of all second-, third-, and fourth-year Ph.D. candidates in inorganic chemistry. Students present their research progress in written and oral forms (A); present a seminar in the literature of the field of research (B); and formulate, write, and orally defend a research proposal (C). Second-year students register for A; third-year students register for B; fourth-year students register for C.
Terms: Win
| Units: 1
CHEM 258B:
Research Progress in Inorganic Chemistry
Required of all second-, third-, and fourth-year Ph.D. candidates in inorganic chemistry. Students present their research progress in written and oral forms (A); present a seminar in the literature of the field of research (B); and formulate, write, and orally defend a research proposal (C). Second-year students register for A; third-year students register for B; fourth-year students register for C.
Terms: Spr
| Units: 1
CHEM 258C:
Research Progress in Inorganic Chemistry
Required of all second-, third-, and fourth-year Ph.D. candidates in inorganic chemistry. Students present their research progress in written and oral forms (A); present a seminar in the literature of the field of research (B); and formulate, write, and orally defend a research proposal (C). Second-year students register for A; third-year students register for B; fourth-year students register for C.
Terms: Aut, Win
| Units: 1
CHEM 259:
Inorganic Chemistry Seminar
Required of graduate students majoring in inorganic chemistry.
Terms: Aut, Win, Spr
| Units: 1
| Repeatable
15 times
(up to 15 units total)
CHEM 271:
Advanced Physical Chemistry
The principles of quantum mechanics. General formulation, mathematical methods, and applications of quantum theory. Exactly solvable problems and approximate methods including time independent perturbation theory and the variational method. Time dependent methods including exactly solvable problems, time dependent perturbation theory, and density matrix formalism. Different representations of quantum theory including the Schrödinger, matrix, and density matrix methods. Absorption and emission of radiation Angular momentum. Atomic structure calculations and simple molecular structure methods. Prerequisite: 175 or equivalent course.
Terms: Aut
| Units: 3
CHEM 273:
Advanced Physical Chemistry
Statistical mechanics is a fundamental bridge that links microscopic world of quantum mechanics to macroscopic thermodynamic properties. We discuss the principles and methods of statistical mechanics from the ensemble point of view. Applications include statistical thermodynamics, quantum systems, heat capacities of gases and solids, chemical equilibrium, pair correlation functions in liquids, and phase transitions. Prerequisite: 271.
Terms: Win
| Units: 3
CHEM 274:
Electrochemical Measurements Lab (CHEM 174)
Introduction to modern electrochemical measurement in a hands-on, laboratory setting. Students assemble and use electrochemical cells including indicator, reference, working and counter electrodes, with macro, micro and ultramicro geometries, salt bridges, ion-selective membranes, electrometers, potentiostats, galvanostats, and stationary and rotated disk electrodes. The later portion of the course will involve a student-generated project to experimentally characterize some electrochemical system. Prerequisites: 134, 171, MATH 51, PHYSICS 44 or equivalent.
Terms: Aut
| Units: 3
CHEM 275:
Advanced Physical Chemistry
Covering angular momentum theory with a special emphasis on scattering dynamics and the interaction of radiation and matter. Recommended: Chem 273 and either Chem 271 or Physics 230.
Terms: Spr
| Units: 3
| Repeatable
2 times
(up to 6 units total)
CHEM 277:
Materials Chemistry and Physics
Topics: structures and symmetries and of solid state crystalline materials, chemical applications of group theory in solids, quantum mechanical electronic band structures of solids, phonons in solids, synthesis methods and characterization techniques for solids including nanostructured materials, selected applications of solid state materials and nanostructures. May be repeated for credit.
Terms: Win
| Units: 3
| Repeatable
2 times
(up to 6 units total)
CHEM 278A:
Research Progress in Physical Chemistry
Required of all second- and third-year Ph.D. candidates in physical and biophysical chemistry and chemical physics. Second-year students present their research progress and plans in brief written and oral summaries (A); third-year students prepare a written progress report (B). A: Win, B: Win
Terms: Win
| Units: 1
CHEM 278B:
Research Progress in Physical Chemistry
Required of all second- and third-year Ph.D. candidates in physical and biophysical chemistry and chemical physics. Second-year students present their research progress and plans in brief written and oral summaries (A); third-year students prepare a written progress report (B). A: Win, B: Win
Terms: Win
| Units: 1
| Repeatable
2 times
(up to 2 units total)
CHEM 279:
Physical Chemistry Seminar
Required of graduate students majoring in physical chemistry. May be repeated for credit.
Terms: Aut, Win, Spr
| Units: 1
| Repeatable
15 times
(up to 15 units total)
CHEM 280:
Single-Molecule Spectroscopy and Imaging
Theoretical and experimental techniques necessary to achieve single-molecule sensitivity in laser spectroscopy: interaction of radiation with spectroscopic transitions; systematics of signals, noise, and signal-to-noise; modulation and imaging methods; and analysis of fluctuations; applications to modern problems in biophysics, cellular imaging, physical chemistry, single-photon sources, and materials science. Prerequisites: 271, previous or concurrent enrollment in 273.
Last offered: Autumn 2005
| Units: 3
CHEM 287:
Chemistry of Posttranslational Modification of Proteins (CHEM 187)
This short course runs for the first four weeks of the quarter, January only. This course examines the chemical principles and mechanisms of major classes of covalent PTMs. Up to 2000 enzyme catalysts are dedicated to PTM creation and reversal, including phosphorylations, acylations, alkylations, glycosylations, oxygenations, automodifications such as green fluorescent protein formation, and controlled proteolysis, including protein splicing. The different PTM chemistries both constrain and enable the diverse biological functions of modified protein substrates. Prerequisite: Chem 181 or equivalent.
Last offered: Winter 2015
| Units: 1
| Repeatable
2 times
(up to 2 units total)
CHEM 287A:
Antibiotics: Actions, Origins, Resistance (CHEM 187A)
This course provides a chemocentric view of three central aspects of antibiotics: (1) antibiotics can come from natural microbial sources or by medicinal chemistry efforts; (2) the mechanism of action of types of clinically used antibiotics towards five major target classes in pathogenic bacteria are assessed; (3) the widespread utilization of antibiotics selects for resistant bacterial pathogens: resistance mechanisms and possible solutions for next generation pathogens are addressed. This short course runs for the first five weeks of the quarter, from January through the first week of February. Prerequisite: Chem 181 or equivalent.
Terms: Win
| Units: 1
| Repeatable
3 times
(up to 3 units total)
CHEM 291:
Introduction to Nuclear Magnetic Resonance
Introduction to quantum and classical descriptions of NMR; analysis of pulse sequences and nuclear spin coherences via density matrices and the product operator formalism; NMR spectrometer design; Fourier analysis of time-dependent observable magnetization; NMR relaxation in liquids and solids; NMR strategies for biological problem solving. Prerequisite: Chem 173.
Last offered: Autumn 2013
| Units: 3
CHEM 296:
Creating New Ventures in Engineering and Science-based Industries (CHEM 196, CHEMENG 196, CHEMENG 296)
Open to seniors and graduate students interested in the creation of new ventures and entrepreneurship in engineering and science intensive industries such as chemical, energy, materials, bioengineering, environmental, clean-tech, pharmaceuticals, medical, and biotechnology. Exploration of the dynamics, complexity, and challenges that define creating new ventures, particularly in industries that require long development times, large investments, integration across a wide range of technical and non-technical disciplines, and the creation and protection of intellectual property. Covers business basics, opportunity viability, creating start-ups, entrepreneurial leadership, and entrepreneurship as a career. Teaching methods include lectures, case studies, guest speakers, and individual and team projects.
Terms: Aut
| Units: 3
CHEM 297:
Bio-Inorganic Chemistry (BIOPHYS 297)
Overview of metal sites in biology. Metalloproteins as elaborated inorganic complexes, their basic coordination chemistry and bonding, unique features of the protein ligand, and the physical methods used to study active sites. Active site structures are correlated with function. Prerequisites: 153 and 173, or equivalents.
Terms: Win
| Units: 3
CHEM 299:
Teaching of Chemistry
Required of all teaching assistants in Chemistry. Techniques of teaching chemistry by means of lectures and labs.
Terms: Aut, Win, Spr
| Units: 1-3
| Repeatable
for credit
CHEM 300:
Department Colloquium
Required of graduate students. May be repeated for credit.
Terms: Aut, Win, Spr
| Units: 1
| Repeatable
15 times
(up to 15 units total)
CHEM 301:
Research in Chemistry
Required of graduate students who have passed the qualifying examination. Open to qualified graduate students with the consent of the major professor. Research seminars and directed reading deal with newly developing areas in chemistry and experimental techniques. May be repeated for credit. Search for adviser name on Axess.
Terms: Aut, Win, Spr, Sum
| Units: 2
| Repeatable
for credit
Instructors: ;
Bao, Z. (PI);
Bent, S. (PI);
Bertozzi, C. (PI);
Boxer, S. (PI);
Burns, N. (PI);
Cegelski, L. (PI);
Chen, J. (PI);
Chidsey, C. (PI);
Cimprich, K. (PI);
Cui, B. (PI);
Cui, Y. (PI);
Dai, H. (PI);
Du Bois, J. (PI);
Fayer, M. (PI);
Frank, C. (PI);
Herschlag, D. (PI);
Hodgson, K. (PI);
Kanan, M. (PI);
Karunadasa, H. (PI);
Khosla, C. (PI);
Kool, E. (PI);
Markland, T. (PI);
Martinez, T. (PI);
Moerner, W. (PI);
Pande, V. (PI);
Pecora, R. (PI);
Rao, J. (PI);
Solomon, E. (PI);
Stack, D. (PI);
Trost, B. (PI);
Wandless, T. (PI);
Waymouth, R. (PI);
Wender, P. (PI);
Xia, Y. (PI);
Zare, R. (PI);
Derner, T. (GP);
Frank, D. (GP)
CHEM 390:
Curricular Practical Training for Chemists
For Chemistry majors who need work experience as part of their program of study. Confer with Chem student services office for signup.
Terms: Sum
| Units: 1
CHEM 459:
Frontiers in Interdisciplinary Biosciences (BIO 459, BIOC 459, BIOE 459, CHEMENG 459, PSYCH 459)
Students register through their affiliated department; otherwise register for CHEMENG 459. For specialists and non-specialists. Sponsored by the Stanford BioX Program. Three seminars per quarter address scientific and technical themes related to interdisciplinary approaches in bioengineering, medicine, and the chemical, physical, and biological sciences. Leading investigators from Stanford and the world present breakthroughs and endeavors that cut across core disciplines. Pre-seminars introduce basic concepts and background for non-experts. Registered students attend all pre-seminars; others welcome. See http://biox.stanford.edu/courses/459.html. Recommended: basic mathematics, biology, chemistry, and physics.
Terms: Aut, Win, Spr
| Units: 1
| Repeatable
for credit
CHEM 802:
TGR Dissertation
Terms: Aut, Win, Spr, Sum
| Units: 0
| Repeatable
for credit
Instructors: ;
Bao, Z. (PI);
Bent, S. (PI);
Bertozzi, C. (PI);
Boxer, S. (PI);
Burns, N. (PI);
Cegelski, L. (PI);
Chen, J. (PI);
Chidsey, C. (PI);
Cimprich, K. (PI);
Collman, J. (PI);
Cui, B. (PI);
Cui, Y. (PI);
Dai, H. (PI);
Du Bois, J. (PI);
Fayer, M. (PI);
Frank, C. (PI);
Herschlag, D. (PI);
Hodgson, K. (PI);
Huestis, W. (PI);
Kanan, M. (PI);
Karunadasa, H. (PI);
Khosla, C. (PI);
Kool, E. (PI);
Markland, T. (PI);
Martinez, T. (PI);
Moerner, W. (PI);
Pande, V. (PI);
Pecora, R. (PI);
Rao, J. (PI);
Solomon, E. (PI);
Stack, D. (PI);
Trost, B. (PI);
Wandless, T. (PI);
Waymouth, R. (PI);
Wender, P. (PI);
Xia, Y. (PI);
Zare, R. (PI);
Derner, T. (GP);
Frank, D. (GP)
