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COMPMED 80N: Animal behavior: sex, death, and sometimes food!

Preference to freshman. Behavior is what makes animals special (thirsty plants don't walk to water), but why do animals behave the way they do? What does their behavior tell us about their inner lives, and about ourselves? What do lipstick and cuckoos and fireflies have in common? Why would nobody want to be a penguin? What do mice say to each other in their pee-mail? Learning how to think about questions like these gives us a unique perspective on the natural world. Format: Flipped, Student-centered, Community of learners, with online and in-person discussion. Discussion and criticism of video examples, and documentaries, and student presentations. Topics: History and approaches to animal behavior; development of behavior, from genetics to learning; mechanisms of behavior, from neurons to motivation; function of behavior, from honest signals to selfish genes; the phylogeny of behavior, from domestication to speciation; and modern applications of behavior, from abnormal behavior, to conservation, to animal welfare, and animal consciousness.
Terms: Aut, Spr | Units: 3 | UG Reqs: WAY-SMA
Instructors: ; Garner, J. (PI)

COMPMED 81Q: Aardvarks to Zebras: The A to Z of Animal Anatomy

Preference to sophomores. Ever wonder what cats and narwhals have in common? Maybe you haven't, but despite their seemingly different lifestyles and habitats (i.e. sleeping on couches versus swimming in oceans), they are both mammals! In this seminar, students will gain an appreciation for basic mammalian anatomic and physiologic principles that span across multiple species while emphasizing key differences that render each species unique. Through student projects, we will explore evolutionary adaptations that have driven the success of a variety of species within the context of their natural environments. In addition to a weekly lecture, anticipated laboratory sessions will reinforce anatomic principles through a combination of rodent cadaver dissection, organ and bone specimens, and use of virtual reality demonstrations. Furthermore, as conditions allow, students will have the opportunity to visit Año Nuevo State Park to experience a guided viewing of northern elephant seals within their natural habitat. Students with a passion for science will gain a fundamental understanding of anatomy that is applicable to future careers in medicine, biomedical research, veterinary medicine, and ecology/conservation.
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Casey, K. (PI)

COMPMED 84Q: Globally Emerging Zoonotic Diseases

Preference to sophomores. Infectious diseases impacting veterinary and human health around the world today. Mechanisms of disease, epidemiology, and underlying diagnostic, treatment and control principles associated with these pathogens. ***This course will be offered in AY 23-24.***
Terms: Spr | Units: 3 | UG Reqs: WAY-SMA
Instructors: ; Felt, S. (PI)

COMPMED 89SS: The Neurobiology of Pain

Whether from the sharp bite of a stubbed toe, the dull throb of an aching muscle, or progressive disease discomfort, pain acts as a natural defense mechanism to protect both humans and animals. It is critical for survival. Pain also serves as a warning against repetitive, harmful behaviors. It's a signal to seek attention and relief, since uncontrolled pain can have chronic and debilitating consequences. This course introduces basic pain concepts, pain pathways, and their underlying neurobiology. Topics will incorporate diagnosis, symptoms and presentation, and treatment using pain experts across the medical field-- such as physicians, veterinarians, dentists, and pharmacists. The course will introduce scientists and clinical researchers, and highlights from their work.
Terms: Sum | Units: 3
Instructors: ; Pacharinsak, C. (PI)

COMPMED 91N: And that's why cats should never eat garlic!

Did you know that although we love garlic, it could make cats very sick? And how come if a human or a dog gets a heart attack they'll end up with a scar, but some fish can regenerate parts of their hearts? In this course, we will explore how select diseases can manifest themselves similarly or differently in different animal species. Students will have the opportunity to interpret physical exam findings, examine blood lab tests (bloodwork), look at X-rays (radiographs), and see what some of these diseases look like at the microscopic level (histology). Students will also discuss how humans benefit from understanding diseases in veterinary species, and how veterinary species benefit from understanding diseases in humans. This course will be of interest to those wanting to learn more about disease processes, and those interested in pursuing careers in biomedical fields including veterinary and human medicine. Oh, and one last thing don't cook with non-stick pans if you have indoor birds. Why? Sign up for the course to find out!
Terms: Spr | Units: 3 | UG Reqs: WAY-SMA
Instructors: ; Vilches-Moure, J. (PI)

COMPMED 110: Pre-Veterinary Advisory

Have you ever considered a career in veterinary medicine but are unsure what it would entail? Pre-Vet Advisory fosters a community of veterinary-curious students and connects them with Stanford veterinarians. Periodic group meetings and guest lectures will introduce students to the variety of career options within veterinary medicine. Academic advising, with an emphasis on required coursework and practical experience, will be provided for those students intending to apply to veterinary school.
Terms: Aut, Win, Spr | Units: 1 | Repeatable for credit
Instructors: ; Casey, K. (PI); Huss, M. (PI)

COMPMED 114: Wielding White Coat Words: Introduction to Comparative Medical Terminology

Are you left clueless trying to understand the medical jargon when watching your favorite medical drama? Are you interested in attending a professional school (e.g., medical, dental, or veterinary) and want to have a head start over your classmates? The Comparative Medical Terminology course is designed to introduce students to a new language of human and veterinary medical terminology. Upon successful completion of the course, students will be able to comprehend a medical record report and to communicate using medical terminology. This course is designed for STEM students who are considering pursuing advanced training in a health care profession and/or translational science or biomedical research. No previous experience using medical terminology is necessary.
Terms: Win | Units: 3
Instructors: ; Bentzel, D. (PI)

COMPMED 182: How to Avoid the Walking Dead: Understanding Biosafety

Are you concerned the Walking Dead will soon rise? Are we on the verge of World War Z? What can be done to prevent the escape of Zombie-producing agents from labs? This course seeks to save the world through the introduction of biosafety history, concepts, and principles & practices as seen through the lens of specific diseases and research at Stanford. The course will be of interest to students looking to pursue careers in biomedical research or those wishing to pursue professional medical education.
Terms: Sum | Units: 2
Instructors: ; Bentzel, D. (PI)

COMPMED 185: Animal Use in Biomedical Research

Preference to freshmen. How and why animals are used in biomedical science. Addresses human and animal disease entities and how animal research has contributed to the treatment and cure of disease. SignificantPreference to freshmen. How and why animals are used in biomedical science. Addresses human and animal health and how animal research has contributed to the treatment and cure of disease. Significant portions of this course are devoted to documenting the humane care and treatment of laboratory animals in research, including, but not limited to such topics as law and ethics, animal behavior, animal modeling, and the animal activist movement. Course topics will also include: history of animals in research, environmental enrichment for research animals, and research animals in the media.
Terms: Spr | Units: 3

COMPMED 198: Undergraduate Directed Reading in Comparative Medicine

May be taken as a prelude to research and may also involve participation in a lab or research group seminar and/or library research.
Terms: Aut, Win, Spr, Sum | Units: 1-3 | Repeatable for credit

COMPMED 199: Undergraduate Research

Investigations sponsored by individual faculty members. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 1-3 | Repeatable for credit

COMPMED 200: One Health Journal Club

Participants report on and review scientific articles published in peer reviewed journals. Focus is on manuscripts which report basic and mechanistic discoveries, animal modeling and translational research. The objective is to introduce MLAS students to critical scientific review of hypothesis-based research and experimental design, data analysis and interpretation. Enrollment limited to undergraduate and graduate students currently matriculated or planning to enroll in the MS in Laboratory Animal Science degree program.
Terms: Aut, Win | Units: 1 | Repeatable 5 times (up to 5 units total)
Instructors: ; Hestrin, S. (PI)

COMPMED 202: Research Biomethodology for Laboratory Animal Science

Emphasis is on providing introductory training and practical, hands-on research animal biomethodology. Topics include basic care and principles guiding the use of research animals, animal health and welfare, enrichment, basic mouse handling, rodent breeding, and the principles of rodent aseptic surgery and anesthesia. The objective of this course is to teach basic skills in animal handling, animal care, and biomethodological research techniques. Content delivered online and in-person.
Terms: Aut, Win, Spr | Units: 1
Instructors: ; Huss, M. (PI)

COMPMED 205: Animal Use in Biomedical Research

How and why animals are used in biomedical science. Addresses human and animal health and how animal research has contributed to the treatment and cure of disease. Significant portions of this course are devoted to documenting the humane care and treatment of laboratory animals in research, including, but not limited to such topics as law and ethics, animal behavior, animal modeling, and the animal activist movement. Course topics will also include: history of animals in research, environmental enrichment for research animals, and research animals in the media. Includes hands-on workshops covering animal handling, aseptic rodent surgery, and mouse breeding.
Terms: Spr | Units: 4
Instructors: ; Albertelli, M. (PI)

COMPMED 209: Laboratory Animal Medicine Seminar

Focuses on husbandry, care, and diseases of major laboratory animal species (rodents, fish and amphibians, swine, sheep, rabbits, monkeys); regulatory and compliance, applied principles of animal modeling, and factors that influence animal research, animal behavior, and research reproducibility. The objective of this course is to provide students with an overview of the history of laboratory animal science, current industry standards and practices, and the fundamentals of laboratory animal diseases. Department consent is required for enrollment. May be repeated for credit. The course is virtual. Must attend 7 out of 10 seminars in the quarter for a satisfactory grade.
Terms: Aut, Win, Spr | Units: 1 | Repeatable 3 times (up to 3 units total)

COMPMED 210: Form and Funkiness of Lab Animals : Anatomy, Histology, and Pathology

Have you ever stopped to think what all those pink and purple dots mean in a histology slide? Does wondering about what a pancreas really looks like keep you up at night? Have you ever lost sleep thinking about what dermatitis or an infarct really are? Well, this is your lucky quarter! This course focuses on the anatomy and histology (microscopic anatomy) of the entire mouse, both in normal and diseased states. The topics covered in the first portion of the course include: 1) organ identification at the gross level, 2) proper tissue fixation and preparation for histology, 3) identification of normal organ histology on hematoxylin and eosin (H&E)-stained slides, and 4) use of special stains for brightfield microscopy. Topics covered in the second portion of the course include: 1) basic pathology principles (response to injury, cell death, inflammation, healing, and neoplasia), and 2) common diseases of the laboratory mouse. This course may involve dissection laboratories. Comfort with mouse handling and previous participation in the VSC Mouse Handling Workshop and the Rodent Tissue Collection and Necropsy Workshop is recommended.
Terms: Aut | Units: 4
Instructors: ; Vilches-Moure, J. (PI)

COMPMED 211: Robust, reproducible, real-world experimental design and analysis for life and biomedical scientists

So you've taken all these stats classes and learned a bunch of equations, but now you have to design and analyze your own experiments, and you're feeling lost and all those equations and classes really don't make sense. DON'T PANIC, we've all been there, and this is the class for you! Try learning these essential skills a different way - conceptually and hands-on without equations. Emphasis is on real-world experimental design and analysis in the life sciences, with particular focus on modern techniques that maximize power and minimize sample size, and avoiding common errors contributing to false discovery and the reproducibility crisis. This is a flipped-classroom. Class time is devoted to discussion of assigned reading (primarily Grafen & Hails 2002 "Modern statistics for the life sciences"), hands on guided work-through of example data sets, and developing analyses for the students' own research data. The objective is to provide students with a foundational conceptual understanding of biostatistics, particularly as applied to the design and planning of animal-based research projects.
Terms: Aut | Units: 3
Instructors: ; Garner, J. (PI)

COMPMED 260: Masters Laboratory Animal Science Practicum/Laboratory Research

Research laboratory and clinical service (pathology, diagnostic laboratory, surgery, husbandry, anesthesiology, aquatics, facility business and management, etc.), quarterly rotations for students enrolled in the Master's of Laboratory Animal Science program. The objective of this course is to provide students with hands on experience in research laboratories using animal models and to provide experience working in the daily operations of a large, veterinary service center. Fulfills the practicum and research requirements of MLAS students.
Terms: Aut, Win, Spr, Sum | Units: 1-18 | Repeatable 6 times (up to 90 units total)

COMPMED 290: Laboratory Animal Science Professional Development and Career Exploration

Focus is on career development for graduate students and trainees enrolled in a trainee program in the Department of Comparative Medicine. Seminar topics include career pathways in laboratory animal science, resume preparation, manuscript preparation and authorship, life in academics, life in industry and biopharma, regulatory agencies, veterinary and medical school. Speakers include faculty, speakers from industry and pharmaceutical companies, veterinary school and medical school graduates, regulatory and compliance professionals, research scientists, and animal research program/laboratory managers. Students may choose to shadow veterinary clinical faculty or rotate through basic science laboratory, by special arrangement. The objective is to introduce students to the multiple career pathways available to individuals with advanced training in laboratory animal science. May be taken up to six quarters.
Terms: Aut, Win | Units: 1 | Repeatable 6 times (up to 6 units total)

COMPMED 299: Directed Reading in Comparative Medicine

Prerequisite: consent of instructor. (Staff)
Terms: Aut, Win, Spr, Sum | Units: 1-18 | Repeatable for credit

COMPMED 370: Medical Scholars Research

Provides an opportunity for student and faculty interaction, as well as academic credit and financial support, to medical students who undertake original research. Enrollment is limited to students with approved projects.
Terms: Aut, Win, Spr, Sum | Units: 4-18 | Repeatable for credit

COMPMED 399: Graduate Research

Investigations sponsored by individual faculty members.Opportunities are available in comparative medicine and pathology, immuno-histochemistry, electron microscopy, molecular genetics, quantitative morphometry, neuroanatomy and neurophysiology of the hippocampus, pathogenesis of intestinal infections, immunopathology, biology of laboratory rodents, anesthesiology of laboratory animals, gene therapy of animal models of neurodegenerative diseases, and development and characterization of transgenic animal models. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 1-18 | Repeatable for credit
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