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COMPMED 10SC: Comparative Anatomy and Physiology of Mammals

This class will provide the student with a deeper appreciation for the diversity of the mammalian orders, along with the fundamentals of comparative anatomy, physiology, and basic dissection techniques. In addition to dissection labs, Dr. B has a large collection of skulls, bones and plastinated organs that will facilitate learning mammalian anatomy. A field trip to the California Academy of Sciences will expose the students to the ¿behind the scenes¿ collection of 1000¿s of mammalian species, and a field trip to a local zoo will enable students to appreciate behavior and locomotion of assorted mammals in their ¿native¿ habitats. Course assignments: There will be 1 exam, 1 short presentation on an evolutionary topic and 1 final power point presentation on a human/animal or animal/animal interaction or conflict. The presentations will highlight animals from the students' assigned mammalian orders. Summer reading assignments will help prepare students for this enjoyable but intensive class. Sophomore College course, applications required. Applications due 12 noon April 5, 2015; apply at http://soco.stanford.edu.
Terms: Sum | Units: 2
Instructors: ; Bouley, D. (PI)

COMPMED 11SC: Life in the Zoo: Behavior, Welfare and Enrichment

Emphasis is on how animal welfare sciences provide an evidence-based approach to optimize and balance each of these demands so that "good welfare is good business." Topics include how to apply principles of animal behavior to design environmental enrichments beneficial to both animals and complex mission of the zoo; assessing exhibits from the point of view of animal behavior and well-being, educational opportunities and guest experience; developing an enrichment plan; designing and building enrichments for animals; interacting with the public as docents; assessing overall effectiveness of new enrichment. Class includes experience at San Francisco Zoo.
Last offered: Summer 2015 | Units: 2

COMPMED 80N: Introduction to Animal Behavior

Preference to freshman. Behavior is what makes animals special (thirsty plants don't walk to water), but why do animals behave the way they do? What does their behavior tell us about their inner lives, and about ourselves? What do lipstick and cuckoos and fireflies have in common? Why would nobody want to be a penguin? What do mice say to each other in their pee-mail? Learning how to think about questions like these gives us a unique perspective on the natural world. Format: Discussion and criticism of video examples, documentaries, and research papers. Topics: History and approaches to animal behavior; development of behavior, from genetics to learning; mechanisms of behavior, from neurons to motivation; function of behavior, from honest signals to selfish genes; the phylogeny of behavior, from domestication to speciation; and modern applications of behavior, from abnormal behavior, to conservation, to animal welfare, and animal consciousness.
Terms: Aut, Spr | Units: 3 | UG Reqs: WAY-SMA
Instructors: ; Garner, J. (PI)

COMPMED 81N: Comparative Anatomy and Physiology of Mammals

Preference to freshmen. Emphasis is on a comparative approach to anatomy and physiology of a wide range of mammals, the unique adaptations of each species in terms of its anatomical, and behavioral characteristics, and how these species interact with human beings and other animals. Dissection required. Class size is limited to 16.
Terms: Win | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Bouley, D. (PI)

COMPMED 83N: Horse Medicine

Preference to freshmen. The most common equine diseases, ranging from colic to lameness are reviewed using problem-oriented approach. Topics include: equine infectious diseases, care of the newborn foal, medical emergencies, and neurological disorders. A lab on the physical and neurological examination of the horse at the Red Barn.
Terms: Spr | Units: 3
Instructors: ; Green, S. (PI)

COMPMED 84Q: Globally Emerging Zoonotic Diseases

Preference to sophomores. Infectious diseases impacting veterinary and human health around the world today. Mechanisms of disease, epidemiology, and underlying diagnostic, treatment and control principles associated with these pathogens.
Terms: Spr | Units: 3 | UG Reqs: WAY-SMA
Instructors: ; Felt, S. (PI)

COMPMED 85N: Animal Use in Biomedical Research

Preference to freshmen. How and why animals are used in biomedical science. Addresses human and animal disease entities and how animal research has contributed to the treatment and cure of disease. Significantnportions of this course are devoted to documenting the humane care and treatment of laboratory animals in research, including, but not limited to such topics as laws and ethics, animal behavior, animal modeling, and the animal activist movement. Course topics will also include: What advances have been made as a result of the use of animals in research? Who conducts animal research? Predominant animal species used in biomedical research, facts and myths; the regulation of biomedical research; housing and care of laboratory animals; why new drugs must be tested; animal use in stem cell research, cancer research and genetically engineered mice; career choices in biomedical research.
Terms: Spr | Units: 3
Instructors: ; Albertelli, M. (PI)

COMPMED 87Q: Introduction to the Mouse in Biomedical Research

Preference to sophomores. Focus is on the laboratory mouse, a widely used and important research model. Topics include the ethics of animal use in research; the natural history, origin and husbandry of the mouse; characteristics of key mouse strains; its anatomy and physiology; common diseases and their effects on research; coat color genetics relative to human diseases; immunodeficient mouse models; and genetic engineering of mice. The laboratory includes necropsy, handling, anesthesia, identification methods, and common research techniques using live and dead mice. Enrollment limited to 14 students.
Terms: Aut | Units: 3 | UG Reqs: GER: DB-NatSci, WAY-SMA
Instructors: ; Nagamine, C. (PI)

COMPMED 88Q: Blood Cells- The Basics

Preference to sophomores. The essential and constant production of new blood cells by the bone marrow. Focus is on fundamentals of the three blood cell types along with white blood cell subtypes. Topics include the microscopic appearance of blood cells in mammalian and non-mammalian species, common morphologic abnormalities of blood cells, and shifts in blood cells that occur in several major diseases of humans and animals. Ideally suited for premed, prevet and Bio-X students, but no biology specialty background required.
Last offered: Winter 2015 | Units: 3 | UG Reqs: WAY-SMA

COMPMED 89Q: Ouch it Hurts! The Comparative Neurobiology of Pain

Preference to sophomores. Focus is on understanding the basic neurobiology of pain pathways. Topics include the physiology, pharmacology, and clinical aspects of effective pain management. In both humans and animals pain is part of the protective mechanisms that prevent further injury to the body. However, if the pain process continues unchecked, it can become extremely detrimental.
Terms: Win | Units: 3
Instructors: ; Pacharinsak, C. (PI)

COMPMED 107: Comparative Brain Evolution (COMPMED 207)

Functional organization and evolution of the vertebrate nervous system. Topics include paleoneurology, cladistic analysis, allometry, mosaic versus concerted evolution, and evolution of brain region structure, connectivity, and neurons. Comparisons between structure and function of vertebrate forebrains including hippocampi. Evolution of the primate visual and sensorimotor central nervous system as related to vocalization, socialization, and intelligence.
Last offered: Autumn 2014 | Units: 4

COMPMED 110: Pre-Vet Advisory

For students interested in a career in veterinary medicine. How to meet the academic and practical experience prerequisites for admission to veterinary school. Networking with other pre-vet students. Periodic group meetings with guest speakers presenting career options in veterinary medicine. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr | Units: 1 | Repeatable for credit

COMPMED 121: Imaging Anatomy in Animal Models

(Same as RADO 121) Introduces engineering and physical science majors to the basic laboratory animal anatomy visualized and targeted with biomedical imaging. Topics include: various imaging modalities (PET, CT, Radiology, MRI, and other optical imaging) and associated depiction of normal organs and skeletal structures in pigs, dogs, rabbits and rodents. Course includes didactic lectures, discussion, imaging labs and gross cadaver examination.
Last offered: Autumn 2013 | Units: 3

COMPMED 198: Undergraduate Directed Reading in Comparative Medicine

May be taken as a prelude to research and may also involve participation in a lab or research group seminar and/or library research.
Terms: Aut, Win, Spr, Sum | Units: 1-3 | Repeatable for credit

COMPMED 199: Undergraduate Research

Investigations sponsored by individual faculty members. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 1-3 | Repeatable for credit

COMPMED 200: Comparative Medicine Seminar and One Health Journal Club

Focus is on animal modeling and translational research that examines animal and human diseases. Teaches critical reading of scientific papers and presentation skills. Participants report on recent scientific articles and provide updates on their own research projects. Enrollment limited to undergraduate and graduate students currently matriculated or planning to enroll in the MS in Laboratory Animal Science degree program.
Terms: Win, Spr | Units: 1 | Repeatable 5 times (up to 5 units total)
Instructors: ; Hestrin, S. (PI)

COMPMED 201: Neuro-Cellular Core (NEPR 201)

Focuses on fundamental aspects of cellular neurophysiology. Topics include exploration of electrophysiological properties of neurons, synaptic structure and function and synaptic plasticity. The course consists of didactic lectures and student-led discussions of classical papers. Incorporates simulation program Neuron. Enrollment restricted to students enrolled in Neurosciences Graduate Program.
Terms: Aut | Units: 2
Instructors: ; Hestrin, S. (PI)

COMPMED 202: Training in Research and Biomethodology for Laboratory Animal Science

Emphasis is on providing introductory training and practical, hands-on workshops for students interested in learning more about research biomethodology and animal models of human and animal disease. Topics include basic care and principals guiding the use of research animals, animal health and welfare, and research animal enrichment, basic mouse handling, rodent breeding, and the principals of rodent surgery and anesthesia. Content delivered online and in-person.
Terms: Win, Spr, Sum | Units: 5 | Repeatable 2 times (up to 10 units total)
Instructors: ; Pacharinsak, C. (PI)

COMPMED 207: Comparative Brain Evolution (COMPMED 107)

Functional organization and evolution of the vertebrate nervous system. Topics include paleoneurology, cladistic analysis, allometry, mosaic versus concerted evolution, and evolution of brain region structure, connectivity, and neurons. Comparisons between structure and function of vertebrate forebrains including hippocampi. Evolution of the primate visual and sensorimotor central nervous system as related to vocalization, socialization, and intelligence.
Last offered: Autumn 2014 | Units: 4

COMPMED 209: Laboratory Animal Medicine Seminar

Focuses on husbandry, care and diseases of laboratory animal species; experimental techniques; statistics; factors that influence animal research and behavior. Course content is divided into seminars over a two-year period. Department consent required for enrollment. May be repeated for credit.
Terms: Win, Spr, Sum | Units: 2 | Repeatable 6 times (up to 12 units total)
Instructors: ; Felt, S. (PI)

COMPMED 210: Introduction to Mouse Histopathology

Focus is on anatomy and histology (microscopic anatomy) of the entire mouse, proper instrument handling and dissection technique, proper tissue fixation, trimming and orientation in cassettes, identification of normal organ histology on H & E-stained slides using a light microscope, use of special stains, and digital image acquisition. Basic pathological processes (inflammation, necrosis, apoptosis, hyperplasia, cancer) and how these manifest in different organs comprises the pathology aspect of this course. Participants present the pathology of their lab's mouse models. Preference to graduate students working with mouse models. Dissection labs. Comfort with mouse handling and previous participation in VSC mouse handling and euthanasia workshops recommended.
Terms: Spr | Units: 3
Instructors: ; Bouley, D. (PI)

COMPMED 215: Synaptic Properties and Neuronal Circuits

Focus is on synapses and circuits in the central nervous system. Objective is to demonstrate how the specific properties of different synapses play a role in the function of neuronal circuits. The main types of synapses are covered, including both ionotropic and metabotropic-receptor-dependent synapses and their related circuits in the CNS. Lectures and student presentations. If taken for 3 units qualifies as a Core Course satisfying requirements in Cellular, Molecular & Developmental Neuroscience in the Neurosciences Graduate Program. Students enrolling for 3 units write an NIH-style proposal on a selected synapse, proposing a study of its properties and related function and presenting the proposal to the class for critique and discussion.
Last offered: Spring 2011 | Units: 2-3

COMPMED 299: Directed Reading in Comparative Medicine

Prerequisite: consent of instructor. (Staff)
Terms: Aut, Win, Spr, Sum | Units: 1-18 | Repeatable for credit

COMPMED 370: Medical Scholars Research

Provides an opportunity for student and faculty interaction, as well as academic credit and financial support, to medical students who undertake original research. Enrollment is limited to students with approved projects.
Terms: Aut, Win, Spr, Sum | Units: 4-18 | Repeatable for credit

COMPMED 399: Graduate Research

Investigations sponsored by individual faculty members.Opportunities are available in comparative medicine and pathology, immuno-histochemistry, electron microscopy, molecular genetics, quantitative morphometry, neuroanatomy and neurophysiology of the hippocampus, pathogenesis of intestinal infections, immunopathology, biology of laboratory rodents, anesthesiology of laboratory animals, gene therapy of animal models of neurodegenerative diseases, and development and characterization of transgenic animal models. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 1-18 | Repeatable for credit

COMPMED 801: TGR Project

| Units: 0 | Repeatable for credit
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