1 - 10 of 16 results for: DBIO

Considers aspects of the developmental biology of human eggs and the first three weeks of human development. Topics include activation of sperm and eggs during the fertilization process, sperm motility and chemotaxis, cell recognition and immuno-contraception, onset of embryonic transcription, control of cell division, ethical and biological limitations to cloning, and the early establishment of pattern in the human embryo. Social and ethical concerns regarding infertility and the use of human pre-embryos in research are also considered. Readings include current review articles from medical and biological literature. Prerequisite: Advanced-placement Biology.

Evolution of the human hand in the context of primate evolution; roles of the human hand in tool use, manufacture, art, music, and communication. Development of the hand: embryonic axes, appearance of the digit program, roles of cell death, molecular bases of normal and abnormal hand patterns. Prerequisite: advanced placement biology.

Students undertake investigations sponsored by individual faculty members. Prerequisite: consent of instructor.

Open to first year Department of Genetics and Developmental Biology students, to others with consent of instructors. Introduction to basic manipulations, both experimental and conceptual, in genetics and developmental biology.

Mechanisms that direct human development from conception to birth. Conserved molecular and cellular pathways regulate tissue and organ development; errors in these pathways result in congenital anomalies and human diseases. Topics: molecules regulating development, cell induction, developmental gene regulation, cell migration, programmed cell death, pattern formation, stem cells, cell lineage, and development of major organ systems. Emphasis on links between development and clinically significant topics including infertility, assisted reproductive technologies, contraception, prenatal diagnosis, multiparity, teratogenesis, inherited birth defects, fetal therapy, adolescence, cancer, and aging.

Primary and current literature in basic and clinical science aspects of assisted reproductive technologies (ART), and demonstrations of current ART techniques including in vitro fertilization and embryo culture, and micromanipulation procedures such as intracytoplasmic sperm injection and embryo biopsy and cryopreservation.Class only may be taken for 1 unit. 2 units includes papers and attendance at clinical demonstrations. 3 units includes a term paper. Recommended: DBIO 201, or consent of instructors.

Current areas of research in developmental biology. How organismic complexity is generated during embryonic and post-embryonic development. The roles of genetic networks, induction events, cell lineage, maternal inheritance, cell-cell communication, and hormonal control in developmental processes in well-studied organisms such as vertebrates, insects, and nematodes. Team-taught. Students meet with faculty to discuss current papers from the literature. Prerequisite: graduate standing, consent of instructor. Recommended: familiarity with basic techniques and experimental rationales of molecular biology, biochemistry, and genetics.

Literature discussion in conjunction with the Frontiers in Biological Research seminar series in which investigators present current work. Students and faculty meet beforehand to discuss papers from the speaker's primary research literature. Students meet with the speaker after the seminar to discuss their research and future direction, commonly used techniques to study problems in biology, and comparison between the genetic and biochemical approaches in biological research.

Principles of genetics underlying associations between genetic variants and disease susceptibility and drug response. Topics include: genetic and environmental risk factors for complex genetic disorders; design and interpretation of genome-wide association studies; pharmacogenetics; full genome sequencing for disease gene discovery; population structure and genetic ancestry; use of personal genetic information in clinical medicine; ethical, legal, and social issues with personal genetic testing. Hands-on workshop making use of personal or publicly available genetic data. Prerequisite: GENE 202, Gene 203 or BIOS 200.