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1 - 10 of 11 results for: BIOPHYS

BIOPHYS 227: Functional MRI Methods (RAD 227)

Basics of functional magnetic resonance neuroimaging, including data acquisition, analysis, and experimental design. Journal club sections. Cognitive neuroscience and clinical applications. Prerequisites: basic physics, mathematics; neuroscience recommended.
Terms: Win | Units: 3 | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: Glover, G. (PI)

BIOPHYS 228: Computational Structural Biology (SBIO 228)

Interatomic forces and interactions such as electrostatics and hydrophobicity, and protein structure in terms of amino acid properties, local chain conformation, secondary structure, domains, and families of folds. How protein motion can be simulated. Bioinformatics introduced in terms of methods that compare proteins via their amino acid sequences and their three-dimensional structures. Structure prediction via simple comparative modeling. How to detect and model remote homologues. Predicting the structure of a protein from knowledge of its amino acid sequence. Via Internet.
Terms: not given this year | Units: 3 | Grading: Medical Option (Med-Ltr-CR/NC)

BIOPHYS 232: Advanced Imaging Lab in Biophysics (APPPHYS 232, BIO 132, BIO 232, MCP 232)

Laboratory and lectures. Advanced microscopy and imaging, emphasizing hands-on experience with state-of-the-art techniques. Students construct and operate working apparatus. Topics include microscope optics, Koehler illumination, contrast-generating mechanisms (bright/dark field, fluorescence, phase contrast, differential interference contrast), and resolution limits. Laboratory topics vary by year, but include single-molecule fluorescence, fluorescence resonance energy transfer, confocal microscopy, two-photon microscopy, and optical trapping. Limited enrollment. Recommended: basic physics, Biology core or equivalent, and consent of instructor.
Terms: Spr | Units: 4 | Grading: Letter or Credit/No Credit
Instructors: Block, S. (PI) ; Schnitzer, M. (PI)

BIOPHYS 241: Biological Macromolecules (BIOC 241, SBIO 241)

The physical and chemical basis of macromolecular function. Forces that stabilize biopolymers with three-dimensional structures and their functional implications. Thermodynamics, molecular forces, structure and kinetics of enzymatic and diffusional processes, and relationship to their practical application in experimental design and interpretation. Biological function and the level of individual molecular interactions and at the level of complex processes. Case studies in lecture and discussion of classic and current literature. Enrollment limited to 30. Prerequisites: None; background in biochemistry and physical chemistry preferred but material available for those with deficiency; undergraduates with consent of instructor only.
Terms: Spr | Units: 3-5 | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: Das, R. (PI) ; Harbury, P. (PI) ; Herschlag, D. (PI) ; Weis, W. (PI)

BIOPHYS 242: Methods in Molecular Biophysics (SBIO 242)

Experimental methods in molecular biophysics from theoretical and practical standpoints. Emphasis is on X-ray diffraction, nuclear magnetic resonance, and fluorescence spectcroscopy. Prerequisite: physical chemistry or consent of instructor.
Terms: Win | Units: 3 | Grading: Letter (ABCD/NP)
Instructors: Puglisi, J. (PI) ; Weis, W. (PI)

BIOPHYS 250: Seminar in Biophysics

Required of Biophysics graduate students. Presentation of current research projects and results by faculty in the Biophysics program. May be repeated for credit.
Terms: Aut | Units: 1 | Repeatable for credit | Grading: Credit/No Credit
Instructors: Weis, W. (PI)

BIOPHYS 297: Bio-Inorganic Chemistry (CHEM 297)

Overview of metal sites in biology. Metalloproteins as elaborated inorganic complexes, their basic coordination chemistry and bonding, unique features of the protein ligand, and the physical methods used to study active sites. Active site structures are correlated with function. Prerequisites: 153 and 173, or equivalents.
Terms: Win | Units: 3 | Grading: Letter (ABCD/NP)
Instructors: Solomon, E. (PI)

BIOPHYS 300: Graduate Research

Investigations sponsored by individual faculty members. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 1-18 | Repeatable for credit | Grading: Medical Satisfactory/No Credit

BIOPHYS 399: Directed Reading in Biophysics

Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 1-18 | Repeatable for credit | Grading: Medical Satisfactory/No Credit

BIOPHYS 801: TGR Project

Terms: Aut, Win, Spr, Sum | Units: 0 | Repeatable for credit | Grading: TGR
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